Open toxicology concept keeps your screening and research workflows up-to-date
Modern ion trap systems offer solid advantages to the user in a rapidly changing world of mass spectrometry. Easy to use and extremely robust, they deliver the fastest MSn results at all-time sensitivity.
Screen, identify & semi-quantify Known & Unknown targets with much more confidence
Identified Polar, a nonpolar compound in a single run
>12 min Run & Analysis time (Sample to Report)
Curated Library & Methods for over 6000+ Toxicology relevant compounds & their metabolites
New compound can be added in few clicks
UHPLC combined with true MSn and comprehensive Drug Libraries
Simplicity, speed and confidence by true MSn
The Toxtyper system identifies compounds based on MS, MS2 and MS3 spectra plus retention time information, providing confident results and minimizing time for data mining
Reproducibility and transferability through SmartFrag
Data-dependent MSn acquisition using Bruker’s patented SmartFrag technology enables the successful analysis of different types of compounds, regardless of their chemical nature, concentration, or sample matrix.
User interface designed even for non-MS experts
Push-button sample submission and analysis requires minimal user training and allows for 24/7 operation
High Confidence Identifications
User interface designed even for non-MS experts
Push-button sample submission and analysis requires minimal user training and allows for 24/7 operation
Simplicity, Speed and Confidence by true MSn
The Toxtyper system identifies compounds based on MS, MS2 and MS3 spectra plus retention time information, providing confident results and minimizing time for data mining
Reproducibility and Transferability through SmartFrag
Data-dependent MSn acquisition using Bruker’s patented SmartFrag technology enables the successful analysis of different types of compounds, regardless of their chemical nature, concentration, or sample matrix.
Rapid Toxicology Screening
Bruker Toxtyper - High Performance Screening for Toxicology
Featured Videos
Featured Applications
Forensic Toxicology
Clinical Toxicology
Food and Environmental Toxicology
An instrument for every need:
Integrated benchtop system for Research Labs
For Core Labs and High Sample Throughput
nCounter Life Science Assays:
nCounter Elements™:
Expandable with Additional Prep Station:
Enterprise Package:
PROSIGNA optional add-on:
Runs Per Day:
Throughput (Lanes Per Day):
Hands on Time:
Reaction Volume Required:
Linear Dynamic Range:
Throughput:
Yes
Yes
No
No
No
2
24
10 mins
Up to 35 µl
6 x10* total count
12 lanes/6 hours
Yes
Yes
Yes
Yes
No
4*
48-96*
15 mins
Up to 30 µl
7 x10* total count
12 lanes/2.5 hours
nCounter Sprint
nCounter Flex
Product Comparison
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UHPLC combined with true MSn and comprehensive drug libraries
Powerful integration:
The IR Biotyper and Bruker’s MALDI Biotyper can now be combined into a single seamless workflow. Data from the MALDI Biotyper® – which uses MALDI-TOF MS to identify microorganisms to species or genus level within a few minutes – can be imported into the IR Biotyper software, and once analyzed, the entire set of results can be exported to the laboratory’s LIMS in CSV format.
Simple Workflows for Rapid Processing
Analysis by DART-MS relies on a gas-phase ionization mechanism. Initial generation of the ionizing species is by a corona discharge with helium or nitrogen which delivers excited gas atoms that, upon their release into the atmosphere, initiates a cascade of gas-phase reactions. This results in reagent ions created from atmospheric water or (solvent) vapor in the vicinity of the surface subject to analysis where they affect a chemical ionization process. DART ionization processes can generate positive or negative ions, predominantly even-electron specie
Comprehensive Solutions for Every Workflow
Today's forensic toxicology and clinical research labs are challenged by demands for fast and accurate results, along with lab efficiency and cost reduction. Further precise results from the continuous emergence of new drugs into the market, requiring frequent updates of sample screening methods. Easy to use, flexible, and reliable screening and analysis techniques are clearly needed to address these demands. The Toxtyper is a powerful “push button solution” for rapid toxicology screening with a simplified, intuitive user interface. The Toxtyper solution was developed to meet the needs of forensic and clinical research labs. Advantages of Toxtyper which includes pre-optimized methods and validated libraries of >1180 drugs and their metabolites. In addition, the Toxtyper supports the ‘Maurer/Wissen bach/Weber LC-MSn library’ containing almost 6000 drugs and metabolites.
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